For this study, the 3D brain organoid was used to model the effects of oxygen deprivation and inflammation on blood brain barrier function to better understand what is happening in a human brain during an ischemic stroke.
Newly discovered pathway may have potential for treating heart failure - New research model helps predict heart muscle cells' impact on heart function after injury - New mass spectrometry approach generates libraries of glycans in human heart tissue - Understanding heart damage after heart attack and treatment may provide clues for prevention - Understanding atrial fibrillation's effects on heart cells may help find treatments - New research may lead to therapy for heart failure caused by ICI cancer medication
In women under 30, thinner and leaner, particularly at the extremes of low body size, does not necessarily equate with better cardiorespiratory fitness. Rather than emphasizing weight loss, better strategies for maximizing athletic performance in young women may include changes in training intensity, training frequency, skill acquisition, competition strategy, sleep and nutrition.
A genetic difference in one gene common in people of East Asian descent may make them more susceptible to rapid heart rates and chemical toxicity if they use e-cigarettes. Although e-cigarettes may have fewer chemicals than tobacco cigarettes, the chemicals in e-cigarette aerosol may still cause harmful effects, particularly in people who are more susceptible because of their genetics.
Among patients hospitalized with abnormal heart rhythms, those with alcohol abuse were 72% more likely to die before being discharged. Strategies to reduce problematic alcohol use may improve the health of patients with irregular heart rhythms and other heart problems.
The rate of seasonal flu vaccinations among people over age 50 and nursing home residents is extremely low, and those who do get the flu vaccine can significantly lower their risk of heart attack, TIA (transient ischemic attack), death and cardiac arrest. Flu vaccination in high-risk patients was associated with a 28% reduced risk of heart attack, a 47% reduced risk of TIA and a 73% reduced risk of death.
A new paper from Penn Medicine shows a low risk of stroke in patients hospitalized for COVID-19. Notably, the majority of afflicted patients had existing risk factors, such as high blood pressure and diabetes. These findings provide more clarity about the role COVID-19 plays in causing stroke in a diverse population of the United States.
In the first study to examine the association between high out-of-pocket costs and adverse cardiovascular events, research led by the Harvard Pilgrim Health Care Institute finds that individuals with cardiovascular disease risk factors who switched to high-deductible health plans (HDHPs) did not experience increased risk of heart attack or stroke. The study, "Association Between Switching to a High-deductible Health Plan and Major Cardiovascular Outcomes" appears in JAMA Network Open on July 24.
TTUHSC's Luca Cucullo, Ph.D., has for years studied the effects smoking and vaping have on the cerebrovascular and neurological systems. He recently led an effort to review the effect smoking and vaping may have on the cerebrovascular and neurological systems of COVID-19 patients. The study, "Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping?" was published May 30 by the International Journal of Molecular Sciences.
Monash researchers have developed a drug that can be potentially given as a preventative against heart attack. The drug -- which has been studied in human cells and animal models -- literally blocks the minute changes in blood flow that preempts a heart attack and acts on the platelets preventing the platelet-triggered clot before it can kill or cause damage.