A vaccine candidate developed at the University of Nebraska-Lincoln has demonstrated promising signs of protection against more than a dozen swine flu strains -- and more than a leading, commercially available vaccine. Its success in experiments involving swine suggests that its design could also fast-track efforts to develop a vaccine that protects people against many common strains of influenza.
Health impacts from a 2010 spill are found even in dolphins born years later.
Disruptions in the circadian rhythms in lung cells may explain why adults who survived premature birth are often more at risk of severe influenza infections, suggests a study in mice published today in eLife.
Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have found that children with multisystem inflammatory syndrome in children (MIS-C) have highly activated immune systems that, in many ways, are more similar to those of adults with severe COVID-19. The results show that better understanding the immune activation in patients with MIS-C could not only help better treat those patients but also improve treatment for adults with severe COVID-19.
Antibiotic-resistant bacteria have become a global threat today, owing in part to the efficiency with which resistance spreads among them. Some of this spread happens in waterbodies--and our wastewater systems are no exception. A group of scientists from Korea and the US has now conducted some of the groundwork needed to optimize disinfection processes and minimize the spread of antibiotic resistance through waterbodies.
Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models. According to new findings published in mBio, the vaccine produced potent neutralizing antibodies among preclinical models and also prevented infection and disease symptoms in the face of exposure to SARS-CoV-2 (the virus that causes COVID-19).
When patients undergo imaging tests for various medical reasons shortly after receiving a COVID-19 vaccine in the arm, their tests may show swollen lymph nodes in the armpit area. Radiologists at Massachusetts General Hospital say that this is usually a normal finding, and they offer recommendations on when and if follow-up tests are needed. The team has published an approach to help avoid delays in both vaccinations and imaging tests.
A new study of patients with Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but severe complication of COVID-19 in children, reveals distinct immune features of COVID-19 not seen in adults that may clue scientists in to why SARS-CoV-2 infection manifests differently in children compared with adults.
Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders. This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders.
At least in cell-based test systems, the plant compound resveratrol has anti-inflammatory properties. A recent collaborative study by the Leibniz Institute of Food Systems Biology at the Technical University of Munich and the Institute of Physiological Chemistry at the University of Vienna has now shown that the bitter receptor TAS2R50 is involved in this effect.