More than 70% of neurological diseases, including Alzheimer's disease and the concussion-related disorder CTE, are believed to be fueled by protein clusters called tau aggregates. A new study sheds light on how they damage brain cells and could ultimately lead to new therapies for such "tauopathies."
Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.
Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers' understanding of factors that affect disease severity and also suggest possible therapeutic options. The genes in question are related to interferons, the body's frontline virus fighters.
One of the most comprehensive statistical analyses of drivers of food insecurity across 65 countries has concluded that household income consistently explains more discrepancy in food security than any other factor, including agricultural land resources and production.
Results suggest vaccination against COVID-19 remains crucial even in young adults who were previously infected.
Russian scientists have proposed a theory of phase transformation in polymer gels. It explains the mechanisms of the dramatic reduction in volume of zwitterionic hydrogels when they are cooled. The results are published in the journal Chemical Communications (ChemComm).
New research sheds light on how autism-spectrum disorder manifests in the brains of girls, prompting the scientists to warn that conclusions drawn from studies conducted primarily in boys should not be assumed to hold true for girls.
Collaborative research of the University of Jyväskylä and Natural Research Institute Finland presents new evidence of the effects of enriched rearing on well-being of aquaculture fishes. The research demonstrates that stone enrichments that have been previously conditioned in lake water significantly improve survival of fish compared to clean stones. Also a higher number of stones has a similar positive effect. The results have practical implications for prevention of aquaculture diseases. The study was published in Antibiotics in March 2021.
Research in the Peruvian Andes highlights critical climate threats to montane forests and urges for current conservation plans to take climate projections into account.
The study has demonstrated the involvement of a new Ca2+ ion entry pathway in angiogenesis processes and the formation of new blood vessels. This Ca2+ pathway is known as SOCE (store operated Ca2+ entry).