The synthesis of silica particles, used in bioimaging and drug delivery, could become considerably cheaper and more efficient by adopting a new flow synthesis method demonstrated by researchers in Australia and China, which involves a spiral channel and simple Teflon pipe to promote the rapid mixing of precursor fluids.
Researchers from the University of Tsukuba have found that flame-sterilizing shake-flasks, to avoid introducing microbial contaminants, considerably increases the carbon dioxide concentration in the flasks. This enhanced carbon dioxide concentration affects the growth of some microbial species, which may affect the quantity of vaccines or other valuable substances produced by the microbes.
When two cars collide at an intersection -- from opposite directions -- the impact is much different than when two cars -- traveling in the same direction -- 'bump' into each other. In the laboratory, similar types of collisions can be made to occur between molecules to study chemistry at very low temperatures, or 'cold collisions.' A team of scientists led by Arthur Suits at the University of Missouri has developed a new experimental approach to study chemistry using these cold 'same direction' molecular collisions.
Researchers at Columbia Engineering and the University of Wisconsin-Madison have identified a library of molecules that shut down the SARS-CoV-2 polymerase reaction, a key step that establishes the potential of these molecules as lead compounds to be further modified for the development of COVID-19 therapeutics. Five of these molecules are already FDA-approved for use in the treatment of other viral infections including HIV/AIDS, cytomegalovirus, and hepatitis B.
Spider silk is useful for a variety of biomedical applications: It exhibits mechanical properties superior to synthetic fibers for tissue engineering, and it is not toxic or harmful to living cells. One unexpected application for spider silk is its use in the creation of biocompatible lenses for biological imaging applications. Researchers describe the feasibility of creating lenses capitalizing on the properties of natural spider silk material in the Journal of Applied Physics.
Scientists at NIBIB have developed new image processing techniques for microscopes that can reduce post-processing time up to several thousand-fold.
Research from the McKelvey School of Engineering at Washington University in St. Louis has shown that understanding brain activity as a network instead of readings from an EEG allow for more accurate and efficient detection of seizures in real-time.
Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the progression of esophageal cancer and liver cancer and it could be a promising target for cancer drug development.
More energy-efficient wastewater treatment may be possible by harnessing anammox bacteria's surprising ability to 'breathe' solid-state matter.
For a wide variety of reasons, zebrafish are one of the most widely used animal models for drug-testing related to neurological disorders. In a breakthrough study, researchers from the Daegu Gyeongbuk Institute of Science and Technology, Korea, have developed the first system that can effectively measure brain activity in multiple adult zebrafish simultaneously, opening doors to the much faster and low-cost testing of drugs for neurological diseases such as epilepsy.