Research reveals that viruses known as bacteriophages that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope in the ongoing battle against antibiotic resistance, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.
A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP). The study, published in the Journal of Bone and Mineral Research and performed in a murine model of the disease, further supports advancing the therapy toward human clinical trials.
Researchers at Tel Aviv University discovered a process by which a "good" virus selectively destroys the DNA of "bad" bacteria, thereby stopping its reproduction. The discovery may assist in the development of treatments against antibiotic-resistant bacteria that cause infectious diseases.
To investigate the role genes play in the evolution of social structure, Rice University researchers created an experiment they likened to the 1998 film 'The Truman Show.' Genetically identical versions of 20 fruit flies were placed in 98 controlled enclosures, and video cameras recorded their interactions. The study in this week's Nature Communications revealed the same clones occupied the same social positions in each enclosure, regardless of living conditions, providing evidence that popularity is heritable.
Frequent caffeine intake could more than triple risk of glaucoma for those genetically predisposed to higher eye pressure.
ETH Zurich researchers have developed a gene switch that can be operated with the green LED light emitted by commercial smartwatches. This revolutionary approach could be used to treat diabetes in the future.
New research has revealed the genetic makeup of the earliest goat herds. The findings, assimilated from DNA taken from the remains of 32 goats that died some 10,000 years ago in the Zagros mountains, provide clues to how early agricultural practices shaped the evolution of these animals.
Research led by the University of Exeter, published in Molecular Psychiatry, also found the most robust evidence to date that being genetically programmed to be an early riser is protective against major depression, and improves wellbeing. Researchers suggest this may be because society is set up to be more aligned to early risers, through the standard 9-5 working pattern.
In an article scheduled to publish in PNAS, on June 7, 2021, at 3 pm ET, a team of researchers led by Columbia University's Dustin R. Rubenstein, a Professor of Ecology, Evolution and Environmental Biology, found that within the same genus of marine snapping shrimp, Synalpheus, genome size and social behavior not only vary widely, but they are also co-evolving over time.
Healthy habits are particularly important during pregnancy. Four new studies being presented at NUTRITION 2021 LIVE ONLINE look at how supplements, eating habits and physical activity can affect various aspects of health during pregnancy.