A fisherman's curiosity led to identification of the correlation between microbial communities in recreational freshwater locales and seasonal environmental changes, according to a team of researchers from Penn State.
Scientists have analyzed the genetic repertoire of bacteria in the human mouth and gut. The effort marks the first chapter in efforts to compile a compendium of all genes in the human microbiome. Mapping the microbial genome can reveal links between bacterial genes and disease risk and could inform the development of precision therapies.
Microbial communities living in deep aquatic sediments have adapted to survive on degraded organic matter, according to a study published in Applied and Environmental Microbiology and coauthored by professors at the University of Tennessee, Knoxville.
A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally focused on mutations in the code for proteins. But now researchers at Western University have shown that the genes encoding tRNAs can also have mutations that cause the code to be misread, and in greater numbers than previously thought.
Walter and Eliza Hall Institute researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced. The team also made the surprising discovery that the immune system protects against different viruses via distinct pathways. Their findings could lead to better strategies to develop vaccines for previously hard-to-prevent viruses.
The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections (STIs) in developed countries. New research by the University of Maryland School of Medicine (UMSOM) shows how the microbiome can either protect or make a woman more susceptible to these serious infections.
Colorado State University researchers found that mosquitoes that could transmit the virus were abundant in feedlots and at nearby sites in Northern Colorado.
University of California, Irvine biologist Joleah Lamb has contributed one of the largest amounts of data to a landmark study on how to save coral reefs in the Indian and Pacific Oceans. She is among more than 80 marine researchers worldwide who produced the report. It has been published in Nature Ecology and Evolution.
A team from the Institut National de la Recherche Scientifique (INRS) has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the immune system. This microorganism is responsible for Leishmaniasis, a chronic parasitic disease that affects more than 12 million people worldwide.
Researchers from the Monash Biomedicine Discovery Institute (BDI) have discovered an antibiotic that could prevent the life-threatening diarrhoea caused by Clostridioides difficile -- a serious bacterial infection often acquired in hospital. The treatment strategy could also potentially counter diseases caused by other similar spore-producing bacteria, including the lethal anthrax, a key bioterrorism tool.