Researchers at the Cluster of Excellence CIBSS - Centre for Integrative Biological Signalling Studies develop technology to introduce genes into single cells in a targeted manner.
Cryo-electron microscopy and computer simulations uncover how a cellular protein helps transport omega-3 fatty acids to the brain and eye, with implications for drug development.
Forsight to present clinical data of their blood-based MRD detection platform for DLBCL that detects relapse 200 days earlier than other methods.
Preclinical research finds that glioblastoma stem cells can be targeted by NK cells, but they are able to evade immune attack by releasing TFG-β. Deleting the TFG-β receptor in NK cells renders them resistant to this and restores their anti-tumor activity.
A new treatment approach focused on fixing cell damage, rather than fighting the virus directly, is effective against SARS-CoV-2 in lab models. Combination of two drugs reduces spread of SARS-CoV-2 infection in cells by up to 99.5%. If found safe for human use, this anti-viral treatment would make COVID-19 symptoms milder and speed up recovery times.
Scientists have identified key molecular events in the developing human embryo between days 7 and 14 -- one of the most mysterious, yet critical, stages of our development.
Researchers from Osaka University, along with international collaborators in Europe, have identified Thrombospondin-2 as a serum biomarker that confirms and stratifies the progressive complications of nonalcoholic fatty liver disease. This research may form the basis of a new noninvasive approach that can provide an early warning system for nonalcoholic steatohepatitis and advanced fibrosis and may predict progression to cirrhosis, liver failure and even cancer.
Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD).
A new study looking at the way human cells activate the immune system in response to SARS-CoV-2 infection could open the door to even more effective and powerful vaccines against the coronavirus and its rapidly emerging variants.
Scientists today track electrical signals and voltage changes in neurons and muscle cells by labeling individual cells or probing with electrodes. UC Berkeley and Stanford scientists have developed a new type of sensor that employs a sheet of graphene to get a continuous measure of electric field in these tissues. Electric fields change graphene's reflectance. The physicists found a way to amplify and measure the changes caused by action potentials in a beating embryonic chicken heart.