In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets.
Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed a technology that produces high-resolution simulations of one of the basic units of our genomes, called the nucleosome. Their findings were published in the journal Nature Protocols and should help improve understanding of how changes in nucleosome folding influence the inner workings of genes.
It might seem like a given than mothers take extra risks to protect their children, but have you ever wondered why? A new study led by Kumi Kuroda at the RIKEN Center for Brain Science (CBS) in Japan shows that in mice, this and other nurturing behaviors are driven in part by neurons in a small part of the forebrain that contain a protein called the calcitonin receptor. The study was published in Cell Reports.
University of Queensland scientists working to unlock the mysteries Australia's deadly stonefish have made a discovery which could change how sting victims are treated in the future.
New research has found that adolescents with higher levels of an omega-3 fatty acid in their blood were less likely to develop psychotic disorder in early adulthood, suggesting that it may have a potential preventative effect of reducing the risk of psychosis.
RNA sequencing is a powerful technology for studying cells and diseases. Scientists from the research group of Christoph Bock, principal investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and professor at the Medical University of Vienna, developed a new method for sequencing huge numbers of single cells in an efficient manner. The study has now been published in Nature Methods.
Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters how high-speed atomic force microscopy can be used for studying DNA wrapping processes. The technique enables visualizing the dynamics of DNA-protein interactions, which in certain cases resembles the motion of inchworms.
Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.
The microscopic algae that live inside and provide nutrients to their reef-building coral hosts may be evolving in tandem with the corals they inhabit. A new study by Penn State biologists reveals that genetic differences within a species of these microalgal symbionts correspond to the coral species they inhabit, a discovery that could have implications for the conservation of these endangered corals.
In collaboration with Kanazawa University, researchers from Osaka City University used high-speed atomic force microscopy (HS-AFM) to visualize at the nanometer level the movement of individual particles within the parasitic bacterium Mycoplasma mobile. After confirming the outline on the surface of the cell structure in an immobilized state with previous data gathered from electron microscopy, the team succeeded in visualizing the real-time movements of the internal structure by scanning the outside of the cell with HS-AFM.