Researchers at the University of Chicago's Pritzker School of Molecular Engineering and Biological Sciences Division have developed a combined imaging and machine learning technique that can, for the first time, measure a metabolic process at both the cellular and sub-cellular levels.
Researchers at the University of Houston, in collaboration with Rice University, published a paper detailing how to improve energy density in a novel electric vehicle battery - a step toward a more cost-effective, easily recycled battery that would allow EVs to travel farther and charge faster at a low cost.
An algorithm designed by researchers from Carnegie Mellon University's Computational Biology Department and St. Petersburg State University in Russia could help scientists identify unknown molecules. The algorithm, called MolDiscovery, uses mass spectrometry data from molecules to predict the identity of unknown substances, telling scientists early in their research whether they have stumbled on something new or merely rediscovered something already known. This development could save time and money in the search for new naturally occurring products that could be used in medicine.
UC San Diego School of Medicine researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.
Additive manufacturing offers an unprecedented level of design flexibility and expanded functionality, but the quality and process can drastically differ across production machines, according to Hui Yang, a professor of industrial engineering at Penn State. With applications in aerospace, health care and automotive industries with potential for mass customization, additive manufacturing needs quality management.
In research published today in Nature Nanotechnology, a team of materials scientists and engineers, led by Jian Shi, an associate professor of materials science and engineering at Rensselaer Polytechnic Institute, used a strain gradient in order to break inversion symmetry, creating a novel optoelectronic phenomenon in the promising material molybdenum disulfide (MoS2) -- for the first time.
In the international prospective multicenter crossover LEADER-75 trial, comparison of reduced-dose gadobutrol and standard-dose gadoterate versus unenhanced imaging demonstrated noninferiority using 20% margin for three primary efficacy measures; mean readings differed by less than 1%, supporting equivalence using a narrow ±5% margin. Various secondary variables also supported non-inferiority of reduced-dose gadobutrol.
Geothermal energy systems have the potential to power the world and become the leading technology for reducing greenhouse gas emissions if we can drill down far enough into the Earth to access the conditions necessary for economic viability and release the heat beneath our feet. Quaise Inc. is developing a potentially disruptive drilling technology to make that happen. Matt Houde of Quaise presented the approach at the World Geothermal Congress on June 15.
Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19. By mimicking the receptor that the virus binds to rather than targeting the virus itself, nanodecoy therapy could remain effective against emerging variants of the virus.
The depths of the Black Sea store comparatively large amounts of organic carbon. A research team led by scientists from the University of Oldenburg, Germany, has now presented a new hypothesis as to why organic compounds accumulate in this semi-enclosed sea and other oxygen-depleted waters. Reactions with hydrogen sulfide play an important role in stabilizing carbon compounds, the researchers posit in the scientific journal Science Advances. This negative feedback in the climate system could counteract global warming over geological periods.