Links between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer's disease. This imbalance inspired researchers to explore the role of lipids comprising the cellular membranes of brain cells. In Biointerphases, the researchers report on the significant role lipids may play in regulating C99, a protein within the amyloid pathway, and disease progression.
Optical cloaking allows objects to be hidden in plain sight by guiding light around anything placed inside the cloak. While cloaking has been popularized in fiction, researchers in recent years have started realizing cloaks that shield objects from view by controlling the flow of electromagnetic radiation around them. In Journal of Applied Physics, researchers examined recent progress of developing invisibility cloaks that function in natural incoherent light and can be realized using standard optical components.
Research led by King's College London has, for the first time, shown that when omega-3 polyunsaturated fatty acids (PUFAs) are given to patients with depression they are metabolised into molecules called lipid mediators and the levels of these in the blood are linked to an improvement in symptoms. The research is published today in Molecular Psychiatry.
The information presented in this study is primarily positioned to benefit scientists and experts in Cellular Physiology and Histochemistry where new tools to discover therapeutic targets for muscle atrophy are needed. The study outlines the development of a new fluorescent reporter mouse line to detect changes in mitophagy activity. These findings could revolutionize treatment strategies and possibly facilitate interventions to reverse disuse-induced muscle atrophy.
State-of-the-art video microscopy has enabled Australian researchers to see the molecular details of how malaria parasites invade red blood cells - a key step in the disease.
Many cosmetics sold in the United States and Canada likely contain high levels of per- and polyfluoroalkyl substances (PFAS), a potentially toxic class of chemicals linked to a number of serious health conditions, according to new research from the University of Notre Dame.
A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer's disease, a new study shows.
Makeup wearers may be absorbing and ingesting potentially toxic per- and polyfluoroalkyl substances (PFAS), according to a new study. The researchers found high fluorine levels--indicating probable presence of PFAS--in about half of makeup tested. Some products underwent further analysis and were all confirmed to contain at least four PFAS of concern. Most products had no PFAS listed on the label.
Study published in PLoS Biology shows that Alzheimer disease experimental papers that omit mice from their titles are linked to more science news stories and gain greater visibility. The finding points to yet another type of spin in the reporting of biomedical research.
Combustion engines can develop high frequency oscillations, leading to structural damage to and unsafe operating conditions. In Physics of Fluids, research clarifies the feedback processes that give rise to these oscillations. The investigators studied simulated combustion events in a computational model of a rocket combustor and their analysis involved sophisticated techniques, including symbolic dynamics and the use of complex networks to understand the transition into oscillatory behavior.