Prematurely born babies often need oxygen therapy to prevent brain damage or death. Unfortunately, excessive oxygen can damage immature lungs and cause severe life-long problems including bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH). A new study in The American Journal of Pathology, published by Elsevier, provides insights into the important role that the hormone adrenomedullin plays in the development, recovery, and prevention of BPD and PH.
A Michigan State University researcher is adding new evidence to the argument that the fat around our arteries may play an important role in keeping those blood vessels healthy. The finding could affect how researchers test for treatments related to plaque buildup in our arteries, or atherosclerosis, an issue that can often lead to a heart attack, which is currently a leading cause of death in the United States.
After 50 years of research and the testing of over 1,000 drugs, there is new hope for preserving brain cells for a time after stroke. Treating acute ischemic stroke patients with an experimental neuroprotective drug, combined with a surgical procedure to remove the clot improves outcomes as shown by clinical trial results published today in The Lancet.
In a comparison of 0.25mg/kg and 0.40mg/kg doses of the newer and more convenient clot-busting medication tenecteplase, there was no advantage in increasing the dose above 0.25mg/kg in stroke patients who planned to have mechanical clot retrieval. In addition, administering tenecteplase may decrease the need for mechanical clot removal.
A new, non-invasive wearable magnetic device that stimulates the brain to rewire itself is safe and could improve recovery for stroke survivors. The technology could be a step to help improve motor function after stroke.
Placing stents in cholesterol-clogged brain arteries may be an option to reduce the risk of a repeat stroke. However, it is too soon to know if stenting in the brain arteries improves long-term patient outcomes.
Stroke patients were more likely to get clot-busting treatment and received it faster if treatment started in a mobile stroke unit, an ambulance specially equipped to provide treatment. Those treated in a mobile stroke unit had less post-stroke disability, a German study found.
In a new study, a team of BIDMC researchers evaluate how hospitals awarded for high quality cardiovascular care by the AHA/ACC performed under federal value-based programs.
New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals. This is the result of a new ground-breaking research study, published in the journal Cell. A study that may help to explain why there are, for instance, more severe graft rejections of lung transplants compared to other organs.
A multi-institution study led by the Yale School of Medicine and University of Alabama-Birmingham has attempted to tease out the relative impact of two variables most often linked to life expectancy -- race and education -- by combing through data about 5,114 black and white individuals in four US cities.