Researchers have discovered that anti-obesity medications such as phentermine and topiramate, used individually or in combination, can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery, according to a retrospective study published online in Obesity, the flagship journal of The Obesity Society.
Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients. The study, which will be published May 22 in the Journal of Experimental Medicine, suggests that targeting this pathway with a drug already in phase 2 clinical trials for diabetes could prevent this syndrome.
New findings published in the Journal of Internal Medicine reveal altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes.
Penn State researchers found that adding six grams of spices to a meal high in fat and carbohydrates resulted in lower inflammation markers hours later.
A person affected by this disease has to follow a low-protein diet all his life. Otherwise, phenylalanine will accumulate in the body and can lead to severe damage to the central nervous system.
Why can some people eat as much as they want, and still stay thin? In a study published today in the journal Cell, Life Sciences Institute Director Dr. Josef Penninger and a team of international colleagues report their discovery that a gene called ALK (Anaplastic Lymphoma Kinase) plays a role in resisting weight gain.
In a study publishing May 21 in the journal Cell, researchers use a genetic database of more than 47,000 people in Estonia to identify a gene linked to thinness that may play a role in resisting weight gain in metabolically healthy thin people. They show that knocking out this gene results in thinner flies and mice and find that expression of it in the brain may be involved in regulating energy expenditure.
When researchers asked prospective study participants who they would like to see in videos promoting healthy lifestyle behaviors, the answer was unequivocal: They wanted to see themselves -- that is, other mothers living in low-income households who were overweight or obese. The researchers obliged. And the intervention they designed produced the desired results when it came to improving participants' diet.
A new study from Lund University in Sweden has shown no correlation between obesity and how close you live to fast food restaurants or gyms. Studies from other countries have previously indicated that these factors may be important in adult obesity.
Low-carb, high-fat ketogenic diets, which have attracted public interest in recent years for their proposed benefits in lowering inflammation and promoting weight loss and heart health, have a dramatic impact on the microbes residing in the human gut, collectively referred to as the microbiome, according to a new UC San Francisco study of a small cohort of volunteer subjects.