Within a month following a heart attack, people are at increased risk for a second one. As a result, physicians treat these patients with medications to rapidly reduce cardiovascular risk factors for another event. Although statins are designed to reduce the risk from one underlying problem, low-density lipoprotein (LDL) or "bad" cholesterol, they often aren't able drop it to recommended levels within 30 days.
Biomedical engineers at Duke University have shown that different strains of the same bacterial pathogen can be distinguished by a machine learning analysis of their growth dynamics alone, which can then also accurately predict other traits such as resistance to antibiotics. The demonstration could point to methods for identifying diseases and predicting their behaviors that are faster, simpler, less expensive and more accurate than current standard techniques.
Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, published today in the Journal of Experimental Medicine (JEM), also suggests that, rather than protecting the lungs, key antiviral signaling proteins may actually cause much of the tissue damage associated with COVID-19.
A recently identified mechanism in the immune system reveals a previously unknown protein that could provide an opening to a better understanding of infections and autoimmune diseases. This is shown by a new basic research study from Aarhus University, Denmark.
Resistance to artemisinin, the main component of the current antimalarial treatments recommended by WHO, is already widespread in South-East Asia, but it had not previously been described in Africa. Scientists from the Institut Pasteur recently detected the emergence and spread of malaria parasites capable of resisting artemisinin derivatives for the first time in Rwanda.
Researchers in China identified four key population categories useful in guiding COVID-19 public health policies aimed at minimizing the spread of the disease and reducing fatalities. The team, led by Dr. Baoguo Jiang of the Department of Orthopedics & Traumatology at Peking University People's Hospital, published their findings in the journal Precision Clinical Medicine on May 28.
JAMA Surgery Editor Melina Kibbe, M.D., writes in this editorial: "The implications of these data demonstrating that fewer women are submitting manuscripts to JAMA Surgery during the pandemic are potentially far reaching. First and foremost, the adverse effect of the pandemic on the academic career progression of women may be significant.
New system infuses 'R0' models with climate information to help public health agencies forecast places and times when environmental conditions might enhance transmission of dengue, Zika and other Aedes-borne diseases
As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they're exposed. A new study suggests luring the virus with a decoy -- an engineered, free-floating receptor protein - binds the virus and blocks infection.
A new study led by scientists at La Jolla Institute for Immunology (LJI) shows that memory helper T cells that recognize common cold coronaviruses also recognize matching sites on SARS-CoV-2, the virus that causes COVID-19.