Enteroviruses are one of the most common human pathogens leading to high number of acute and chronic infections worldwide. The physiological events leading to successful enterovirus infection are still poorly understood. Researchers at the Nanoscience Center at the University of Jyväskylä and at the University of Helsinki have found significant new information concerning the role of Albumin and ions in host cell vesicles that promote genome release and efficient infection. The research was published in the Journal of Virology in August.
The discovery could one day let doctors prevent the infection by allowing E. coli to pass harmlessly through the body.
'Coprolites' from the Must Farm archaeological excavation in East Anglia, UK, shows the prehistoric inhabitants were infected by parasitic worms that can be spread by eating raw fish, frogs and shellfish.
A study led by researchers from the University of Illinois at Chicago has found that combining acyclovir -- a commonly prescribed topical herpes medication -- with particles of activated carbon improves efficacy of the drug.
Giving children an additional dose of rotavirus vaccine when they are nine months old would provide only a modest improvement in the vaccine's effectiveness in low-income countries, according to a new study led by the Yale School of Public Health and the Institute of Infection and Global Health at the University of Liverpool.
Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more susceptible to some common antibiotics.
A FAPESP-funded study with results published in The Lancet Infectious Diseases has identified markers capable of predicting mortality in patients with symptoms of yellow fever, potentially helping to prevent the development of severe conditions.
A team led by the Walter Reed Army Institute of Research has gained new insights into the mechanism of vaccine-induced T cell immunity, including regulation, gene expression and metabolic pathways. This study, published in Nature Communications, used samples from a Phase 1 clinical trial for TAK-003, a live-attenuated tetravalent dengue vaccine. Though these discoveries occurred in the context of a dengue vaccine trial, they are applicable to the development of vaccines for numerous viral diseases.
Patients with Lyme disease in England and Wales hospitals appear to be predominantly white, female and living in areas of low deprivation, according to a study published in the open access journal BMC Public Health.
New research led by scientists at The Rockefeller University in New York may help explain why Zika virus infection causes birth defects in some children but not others. The study, which will be published August 14 in the Journal of Experimental Medicine, suggests that the risk of developing an abnormally small head (microcephaly) depends on the types of antibody produced by pregnant mothers in response to Zika infection.