Current treatments for tuberculosis (TB) are very effective in controlling TB infection caused by Mycobacterium tuberculosis (Mtb). They don't, however, always prevent reinfection. Why this happens is one of the long-standing questions in TB research. A team of scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University may have found the answer... in the gut.
There are currently more than three million people in the US with hepatitis C, a condition that can lead to serious and even deadly liver complications. In the US prison system, the prevalence of hepatitis C virus (HCV) infection is currently 10 times higher than the national average. However, new research in the INFORMS journal Operations Research, has identified new protocols that could substantially decrease HCV infection in the US prison system.
A sophisticated new analysis too incorporating advanced mathematical strategies could help revolutionize the way researchers investigate the spread and distribution of dangerous, fast-evolving disease vectors.
To commemorate World TB Day, a Special Collection has been released by PLOS Medicine containing a series of articles that articulate the essential new steps in clinical research that will pave the way for the development of tomorrow's optimal treatment for all forms of tuberculosis.
Beware the ball pit. Ball pits used in children's physical therapy -- similar to those made popular by restaurants catering to families -- may contribute to germ transmission between patients, according to new research published in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology, published by Elsevier.
Rice University scientists build a model to predict how long, on average, it takes to eradicate a bacterial infection with antibiotics. The model could help doctors fight resistance by prescribing antibiotics that neither over- or under-dose a patient.
Researchers have described a new mechanism by which influenza A viruses (IAV) alter the host immune system and make them more or less susceptible to often deadly co-occurring bacterial infections.
Doctors should think carefully before testing patients for a urinary tract infection (UTI) to avoid over-diagnosis and unnecessary antibiotic treatment, according to updated asymptomatic bacteriuria (ASB) guidelines released by the Infectious Diseases Society of America (IDSA) and published in Clinical Infectious Diseases.
Pitt scientists find a viral anti-vaccination Facebook campaign wasn't 'all about autism,' but instead centered on four distinct themes.
Immune cells called inflammatory monocytes are often one of the first responders to infections, but they actually facilitate the progression of Cryptococcus neoformans infection in mice, according to a study published March 21 in the open-access journal PLOS Pathogens by Lena Heung and Tobias Hohl of Memorial Sloan Kettering Cancer Center. According to the authors, these disparate results indicate that inflammatory monocytes possess a plasticity of function that can regulate infection outcomes, making them an important target for immunomodulatory therapies against C. neoformans.