Prematurely born babies often need oxygen therapy to prevent brain damage or death. Unfortunately, excessive oxygen can damage immature lungs and cause severe life-long problems including bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH). A new study in The American Journal of Pathology, published by Elsevier, provides insights into the important role that the hormone adrenomedullin plays in the development, recovery, and prevention of BPD and PH.
Traditional stoves that burn biomass materials and are not properly ventilated, which are widely used in developing nations where cooking is done indoors, have been shown to significantly increase indoor levels of harmful PM2.5 (miniscule atmospheric particulates) and carbon monoxide (CO) and to stimulate biological processes that cause lung inflammation and may lead to chronic obstructive pulmonary disease (COPD), according to new research published online in the Annals of the American Thoracic Society.
Superbug infections kill 35,000 people in the US annually. A team of researchers has found that a treatment known as AB569 kills pseudomonas aeruginosa in humanized cells in mouse models. The treatment does not harm these humanized cells.
Millions of people might eventually be spared the embarrassment and extreme isolation caused by wetting themselves, thanks to new research.
People living in Balkan farming villages along the Danube River have long suffered from a unique type of kidney disease known as Balkan endemic nephropathy. Recently, scientists linked the disorder to compounds from a local weed that could be taken up into food crops from the soil. Now, researchers reporting in ACS' journal Environmental Science & Technology have discovered that contaminated groundwater could be another important source of human exposure.
UCLA researchers who previously found that intravenous administration of fish oil can treat a rare but potentially deadly form of liver disease in children have now monitored levels of a small molecule at the center of the disorder to track treatment results.
More than 10,000 uninsured patients sought care at Texas emergency departments for lifesaving kidney dialysis in 2017, incurring more than $21.8 million in hospital costs, according to researchers from UTHealth.
More than 925,000 adults in the National Cancer Database with a new diagnosis of invasive breast, colon or lung cancer were included in this observational study that examined how Medicaid expansion under the Patient Protection and Affordable Care Act (ACA) was associated with insurance status, cancer stage at diagnosis and timely treatment.
The microbiome of our ancestors might have been more important for human evolution than previously thought. By comparing data from prior studies, the authors revealed that an adaptive gut microbiome could have been critical for human dispersal, allowing our ancestors to survive in new geographic areas.
A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may lead to new drugs to treat or prevent lung cancer.