New science uncovers how an unlikely culprit, Porphyromonas gingivalis (Pg) -- the bacterium commonly associated with chronic gum disease -- appears to drive Alzheimer's disease (AD) pathology.
If mice grow up in a stimulating environment, their brain remains adaptable for longer. In fact, not only these mice, but also their offspring, benefit. The offspring also have increased plasticity of the brain - even if they did not grow up in this environment. This is what a team from the Collaborative Research Centre 889 "Cellular Mechanisms of Sensory Processing" at the University of Göttingen has discovered. Results were published in the journal eNeuro.
Fresh insights into the types of cells found in the brains of people with multiple sclerosis could help develop improved therapies, research has found. The study from experts at the University of Edinburgh and the Karolinska Institute focused on cells in the brain that help to repair damage to nerve cells caused by the disease.
Over a year and a half after the successful separation of two infant twins joined at the top of their heads, surgical team leaders report on this dramatic case in the Jan. 24 New England Journal of Medicine. The surgeons describe the innovative devices, elaborate planning and precisely orchestrated teamwork needed to perform the complex separation surgery at Children's Hospital of Philadelphia.
A new study shows that there is a very limited regeneration of cells in the brain of patients diagnosed with multiple sclerosis (MS). These findings underline the importance of treating MS at an early stage of the disease progression, when the affected cells can repair the damage as they are not replaced by new ones. The results are published in the journal Nature by researchers from Karolinska Institutet and Uppsala University in Sweden.
For people in their 20s and 30s, having blood pressure above normal but below the level considered to be high blood pressure, may be linked to loss of brain volume, according to a study published in the January 23, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology.
An international team of researchers led by Cortexyme co-founders Stephen Dominy, M.D. and Casey Lynch detail the role of a common bacterium, Porphyromonas gingivalis (Pg), in driving Alzheimer's disease pathology and demonstrate the potential for small molecule inhibitors to block the pathogen.
Lead exposure in childhood appears to have long-lasting negative effects on mental health and personality in adulthood, according to a study of people who grew up in the era of leaded gasoline. The findings, which will appear Jan. 23 in JAMA Psychiatry, reveal that the higher a person's blood lead levels at age 11, the more likely they are to show signs of mental illness and difficult personality traits by age 38.
Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death. Preclinical detection of prions has proven difficult, but new research suggests skin samples hold early signs of prion disease that precede neurologic symptoms.
ESport teams require preventive care, injury treatment protocols, according to a study in the British Journal of Medicine.