A preclinical in vitro study shows that selected plant-based herbal medicines, especially Ghanaian quinine and Japanese knotweed, work better than antibiotics against the bacterium that causes Lyme disease. These findings represent an important step towards the development of treatments that might be better tolerated and more effective than the current standard of care.
Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived 'mini-brains' to detect harmful side effects of a common drug on the developing brain. Mini-brains are miniature human brain models, developed with human cells and barely visible to the human eye, whose cellular mechanisms mimic those of the developing human brain.
SCN8A encephalopathy, a rare form of childhood epilepsy, could be improved with a treatment already approved for other uses.
Researchers publishing in Current Biology describe the science behind creating lighting to make us all happy and productive indoors. A company is using the technology to create commercial lightbulbs available later this year.
A cutting-edge MRI technique to detect iron deposits in different brain regions can track declines in thinking, memory and movement in people with Parkinson's disease, finds a new UCL-led study published in the Journal of Neurology, Neurosurgery, and Psychiatry.
Researchers explain symptoms associated with Antidepressant Discontinuation Syndrome and provide a schedule for tapering various classes of antidepressants. Patients who stop medication without tapering often experience flulike symptoms, insomnia, nausea, imbalance, sensory disturbances often described as electric shocks or 'brain zaps', and hyperarousal.
A naturally occurring amino acid is gaining attention as a possible treatment for ALS following a new study published in the Journal of Neuropathology & Experimental Neurology. It showed the amino acid, L-serine, successfully reduced ALS-like changes in an animal model of ALS. After exposure to the cyanobacterial neurotoxin, BMAA, vervets developed pathology similar to the earliest stages of ALS in humans. However, vervets that also received the amino acid L-serine had significantly reduced ALS pathology.
Most of the mothers of a child with Down Syndrome born in the Netherlands between 2010-16 have consciously chosen not to have prenatal testing. This may be considered as an informed choice, as the majority of these mothers felt that a child with DS was welcome in their family.
Merely a brief introduction to mindfulness helps people deal with physical pain and negative emotions, a new study by researchers at Yale, Columbia, and Dartmouth shows. The effect of mindfulness was so pronounced, they found, that even when participants were subjected to high heat on their forearm, their brain responded as if it was experiencing normal temperature.
Maternal obesity may increase a child's risk for attention-deficit hyperactivity disorder (ADHD), according to an analysis by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.