Caltech researchers identify the neural processes that make some memories fade rapidly while other memories persist over time.
Caregivers of people with dementia lose between 2.5 to 3.5 hours of sleep weekly due to difficulty falling asleep and staying asleep -- a negative for themselves and potentially for those in their care, according to Baylor University research published in JAMA Network Open.
A team of scientists from MIPT and IBCh RAS studied one hereditary genetic mutation to discover general molecular mechanisms that may lead both to early onset of Alzheimer's disease and to the form of the disease caused by age-related changes in human body. Understanding these mechanisms is necessary for developing new targeted treatments for this neurodegenerative disease that is becoming ever more widespread across the developed countries' aging populations.
University of Michigan research finds people with mild cognitive impairment don't always receive the same, established medical treatment that patients with normal cognitive functioning get when they have a heart attack.
Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't show any symptoms of memory problems, according to findings published in a joint Baycrest-University of Oxford study.
How does the brain find order amidst a sea of noise and chaos? Researchers at the EPFL Blue Brain Project have found the answer by using advanced simulation techniques to investigate the way neurons talk to each other. In a paper published in Nature Communications, they found that by working as a team, cortical neurons can respond even to weak input against the backdrop of noise and chaos, allowing the brain to find order.
A gene that can become mutated and cause a rare balance disorder also regulates the behavior of an enzyme that increases the risk for Alzheimer's disease.
Research into the self-destruction of cells in humans and plants could lead to treatments for neurodegenerative brain diseases and the development of disease-resistant plants. A study co-led by The University of Queensland's Professor Bostjan Kobe identified the role certain proteins play in cellular suicide.
Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer's disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it. The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer's disease, beta-amyloid plaques -- the hallmark pathology of AD -- never formed. Their study will appear Aug. 21, 2019 in the journal Nature Communications.
Cells regularly go through a process called autophagy -- literally translated as 'self-eating' -- which helps to destroy bacteria and viruses after infection. Now new research by the University of Plymouth has shed light on the mechanisms behind autophagy and how it progresses -- particularly relating to a process called liquid-liquid phase separation (LLPS).