Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness. They have discovered that the molecule TLR2, which recognises chemical patterns associated with infection in the body, also seems to play an important role in the development of retinal degeneration. When TLR2 is removed in model systems, a degree of protection is conferred.
Researchers publishing in Current Biology describe the science behind creating lighting to make us all happy and productive indoors. A company is using the technology to create commercial lightbulbs available later this year.
Data from 82 prison inmates treated in a glaucoma clinic at an academic hospital were used in this observational study to report on how treatment and follow-up, including medication adherence, were are managed.
Subconcussive head impacts from sports are those that don't cause symptoms of a concussion. This randomized clinical trial evaluated whether such subconcussive head impacts from soccer-ball headings impaired brain circuitry linking eye and cognitive functions in adult soccer players compared with a control group of players that only kicked the soccer ball.
Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in the New England Journal of Medicine.
Visual acuity--the ability to discern letters, numbers, and objects from a distance--is essential for tasks including recognizing a friend across a room and driving. Researchers previously assumed visual acuity was primarily determined by the eye's optics and the retina's anatomy. University of Rochester researchers show that small eye movements humans aren't even aware of making also play a large role in visual acuity. The research may lead to improved treatments for vision impairments.
Researchers have identified a new protein linked to age-related macular degeneration (AMD) that could offer new hope for the diagnosis and treatment of the disease, which affects over 1.5 million people in the UK alone.
An international team of scientists has identified a protein which is strongly linked to the commonest cause of blindness in developed countries when its levels are raised in the blood.
Visit adherence plays an important role in outcomes for patients with age-related macular degeneration, a Penn Medicine study found.
The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists from the Technical University of Munich (TUM) has now uncovered the precise structure of the alpha-A-crystallin protein and, in the process, discovered an important additional function.