Researchers from EPFL and the University Medical Center Utrecht in the Netherlands have developed an extremely fast optical method for sculpting complex shapes in stem-cell-laden hydrogels and then vascularizing the resulting tissue. Their groundbreaking technique stands to change the field of tissue engineering.
A serious case of the flu can cause lasting damage to the lungs. In a study in mice, researchers from the University of Pennsylvania and colleagues found that transplanting cells from the lungs of healthy animals enhanced healing in others that had had a severe respiratory infection.
Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants. But pluripotency is still a black box for science, controlled by unknown genetic and epigenetic signals. CNIO researchers now uncovers one of those epigenetic signals, after a detective quest that started almost a decade ago.
'The role of mitochondria has been largely ignored in the field of regenerative medicine, but earlier efforts in our lab suggested that they may affect the outcome of stem cell transplants,' said Tobias Deuse, M.D., the Julien I.E. Hoffman Chair in Cardiac Surgery at UCSF and lead author of the new study, published Aug. 19 in Nature Biotechnology.
Nanotechnology developed at Rutgers University-New Brunswick could boost research on stem cell transplantation, which may help people with Alzheimer's disease, Parkinson's disease, other neurodegenerative diseases and central nervous system injuries.
Research from the University of Cincinnati finds that among women who are kidney transplant recipients, Hispanic women have a higher likelihood of pregnancy than white women.
As a medical emergency caused by severe cardiovascular diseases, myocardial infarction (MI) can inflict permanent and life-threatening damage to the heart. A joint research team comprising scientists from City University of Hong Kong (CityU) has recently developed a multipronged approach for concurrently rejuvenating both the muscle cells and vascular systems of the heart by utilizing two types of stem cells. The findings give hope to develop a new treatment for repairing MI heart, as an alternative to heart transplant.
A new study from the University of Eastern Finland shows that the health-related quality of life of most people who have or have a higher risk of knee osteoarthritis remained unchanged over an eight-year trajectory. Worsening of quality of life was associated with several risk factors, such as obesity and smoking, and it also reflected the patient's need for treatment.
Mount Sinai researchers have developed a way to use immunotherapy drugs against treatment-resistant non-Hodgkin's lymphomas for the first time by combining them with stem cell transplantation, an approach that also dramatically increased the success of the drugs in melanoma and lung cancer, according to a study published in Cancer Discovery in July.
Several countries have combated low organ donor counts by implementing a priority rule that pushes registered donors to the front of the line if they ever need a transplant. However, according to a study from the McCombs School of Business at The University of Texas at Austin published today in Management Science, this model has drawbacks.