A new study sought to develop and validate a way to predict the risk of opioid overdose among Medicare beneficiaries with at least one opioid prescription. The model the researchers developed was more effective in predicting risk of overdose than traditional statistical models.
A study from the Massachusetts General Hospital Recovery Research Institute shows that more than a third of individuals who consider themselves in recovery from an alcohol or other substance use disorder continue to suffer from chronic physical disease.
A study that examined older Americans' well-being before and after medical marijuana laws were passed in their state found reductions in reported pain and increased hours worked. The study, co-written by researchers at Johns Hopkins Bloomberg School of Public Health and Temple University, suggests medical marijuana laws could be improving older Americans' health.
Daily cannabis use, especially of high potency cannabis, is strongly linked to the risk of developing psychosis, according to a case-control study from 11 sites across Europe, published in The Lancet Psychiatry journal. In cities where high potency cannabis is widely available, such as London and Amsterdam, a significant proportion of new cases of psychosis are associated with daily cannabis use and high potency cannabis.
Researchers at the Medical University of South Carolina have identified which neurons are responsible for cocaine-seeking behaviors in rodents and where these neurons exert their effects within the brain. Their findings were published in March 13, 2019 issue of The Journal of Neuroscience. This work opens a new line of addiction research that could lead to novel therapeutic approaches for preventing relapse.
Johns Hopkins researchers have discovered that use of the synthetic psychedelic 5-methocy-N,-N-dimethyltryptamine (5-MeO-DMT) appears to be associated with unintended improvements in self-reported depression and anxiety when given in a ceremonial group setting. 5-MeO-DMT is a psychedelic that is found in the venom of Bufo Alvarius toads, in a variety of plants species, and can be produced synthetically.
Only one group of teenagers used marijuana more often after retail sales were legalized in Washington than they did before -- high school seniors who work 11 or more hours per week, according to new research led by a WSU College of Nursing professor.
National and state trends for opioid prescriptions filled at US retail pharmacies are estimated from 2006 through 2017 in this analysis of data from outpatient prescribing records. Each year an average of nearly 234 million opioid prescriptions were filled. Several key measures of opioid prescribing varied among states.
Pain researchers at Washington University School of Medicine in St. Louis have shown in rodents that they can block receptors on brain cells that appear to be responsible for the negative emotions associated with pain, such as sadness, depression and lethargy. The findings could lead to new, less addictive approaches to pain treatment.
Emergency department (ED) visits by people age 65 and older who were identified with opioid misuse and dependence more than tripled between 2006 and 2014, according to new research published by researchers at Towson University. The study also discovered that opioid misuse was associated with an increased number of chronic conditions, greater injury risk, and higher rates of alcohol dependence and mental health diagnoses.