A new study provides insight into what may contribute to men's suicide vulnerability.
Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias? A new study suggests the answer is no. If this is borne out, that result differs from Alzheimer's disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease -- and thus suggests that the role of tau in the pathogenesis of Lewy body dementias is distinct from Alzheimer's disease.
German RABBIT registry data -- Elderly people with rheumatoid arthritis (RA) are generally at increased risk of serious infections. At the same time, some anti-rheumatic treatments have been associated with a higher serious infection risk, but the extent to which older people are exposed to higher risks with some newer classes of therapy is an open question. Results of this study suggest that treatment with new classes of drugs is not associated with an increased risk of serious infection in elderly patients above 70 years of age.
Smartphone apps have proved invaluable for helping people manage chronic pain during the COVID-19 pandemic, but researchers warn that the need for information sharing and education in this area is being neglected.
A decade-long study of distal radius fracture revealed that personalized medicine catering to a patient's individual needs and environment, not age or X-rays, should guide treatment options. This federally funded study is the most intense, collaborative effort to answer a 200-year puzzle about how to treat the most common forearm fracture in older adults.
Scientists have long known the brain's hippocampus is crucial for long-term memory. Now a new Northwestern Medicine study has found the hippocampus also plays a role in short-term memory and helps guide decision-making. The findings shed light on how the hippocampus contributes to memory and exploration, potentially leading to therapies that restore hippocampal function, which is impacted in memory-related aging and neurodegenerative diseases such as dementia, the study authors said.
Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components.
Researchers from Bentley University, in partnership with Waltham Council on Aging in Massachusetts, and as part of a study funded by the National Science Foundation, have been exploring how the elderly use smart speakers at home.
Despite near unanimous objection from its advisory panel, the US Food and Drug Administration (FDA) granted aducanumab approval to treat Alzheimer's disease on June 7, 2021. In a commentary published in Annals of Internal Medicine, a member and former Chair of the advisory panel and an aducanumab site investigator explain why this unprecedented "accelerated approval" is problematic for clinical research and patient care.
"Boomers" and "millennials" who go to church are more likely to trust their neighbours and donate to charity, according to a new study.