Scientists at the University of California, Riverside, have devised potent chemical agents 135H11 and 135H12 that can thwart cancer metastasis, bringing research closer to drug development.
New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure. The findings, published today in the open-access journal eLife, represent the first time the human epithelial sodium channel has been shown so precisely since it was first isolated and described through expression cloning more than two decades ago.
A new technique to increase the efficiency of carbon dioxide (CO2) electrolysis that may lead to the production of new chemicals and fuels.
Princeton University researchers have proposed a US pipeline network that would capture, transport and store underground up to 30 million metric tons of carbon dioxide emissions each year -- an amount equal to removing 6.5 million cars from the road. The authors found that the network infrastructure would only be possible if tax credits passed by Congress in 2018 to encourage investment in carbon capture-and-storage technology are coupled with low-interest government financing.
Researchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania, are developing an artificial bone, which can be used for treating one of the most common joint diseases -- osteoarthritis. The bi-functional composite imitates the complex osteochondral structure of a joint, i.e. both cartilage and bone tissues.
When it comes to changing their passwords, bacteria are just as bad as you and me -- maybe even worse. A Carnegie Mellon University research team has found that despite 2.7 billion years of evolution, bacteria are still using the same 'password' to initiate the process for making spores. Their findings were published in the September issue of PLOS Genetics.
New findings show that a micro RNA from the shoot keeps legume roots susceptible to symbiotic infection by downregulating a gene that would otherwise hinder root responses to symbiotic bacteria. These findings help us understand what it takes to make nitrogen-fixing symbiosis efficient, and what we need to do to exploit it agronomically.
A new auto-commentary looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can be used to improve drug development and personalized medicine.
Scientists at the Medical University of South Carolina have discovered that a protein called VRK1 might help cancer to take root in new parts of the body. In results published in the journal PLOS ONE on Sept. 4, 2018, VRK1 was discovered to be necessary for mesenchymal-to-epithelial transition, which scientists suspect may be important for the establishment of metastasis.
In plants, to fertilize the egg, the pollen tube (which is between 1/20 and 1/5 of the width of a human hair) has to navigate through a maze of tissue, no matter what obstacles it encounters. Thanks to the lab-on-a chip technology scientists were able to actually see and measure exactly what was going on within the pollen tube as it grew.