A new approach could illuminate a critical stage in the life cycle of one of the most common malaria parasites. The approach was developed by scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan and published in the Malaria Journal.
A new technique could help reduce antibiotic prescribing by predicting which drugs could be effective in fighting bacteria within minutes.
A collaboration between the University of Toronto's Faculty of Dentistry and the National Jewish Health in Denver -- the top-ranked respiratory research hospital in the US -- has yielded a new drug discovery that could be useful to combat inflammation of all varieties and shows promise in fighting acute respiratory illnesses such as COVID-19.
New technologies capable of sequencing single molecules in fine detail will help scientists better understand the mechanisms of rare nucleotides thought to play an important role in the progression of some diseases.
Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these proteins suppress B cell function and conversely, that Tet2/Tet3 knockout mice develop a mild form of systemic lupus erythematosus due to hyperactivation of T cells. These findings could help develop a novel treatment for autoimmune diseases.
In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a new method developed at Chalmers University of Technology, Sweden, reveals how the composition of cell membranes seems to be a decisive factor for how small quantities of α-synuclein cause damage.
A study released today in STEM CELLS outlines a new platform researchers designed that allowed them to investigate the potentially harmful effects of microplastics and nanoplastics.
Researchers have solved the mystery of why a species of bacteria that causes food poisoning can swim faster in stickier liquids, such as within guts.
For the first time, scientists have shown that the bacterium that causes the tick-borne disease anaplasmosis interferes with tick gene expression for its survival inside cells and to spread to a new vertebrate host. Girish Neelakanta of Old Dominion University and colleagues report these findings in a study published July 2nd in PLOS Genetics.
Motile sperm are difficult to collect with a conventional cell sorter because they are vulnerable to physical damage. A Japanese research collaboration has developed a technique using a cell sorter with microfluidic chip technology to reduce cell damage and improve in vitro fertilization rates. This research is expected to increase in vitro fertilization rates to improve production of experimental animals and livestock, and could be used as a fertility treatment in reproductive medicine.