Enteroviruses are one of the most common human pathogens leading to high number of acute and chronic infections worldwide. The physiological events leading to successful enterovirus infection are still poorly understood. Researchers at the Nanoscience Center at the University of Jyväskylä and at the University of Helsinki have found significant new information concerning the role of Albumin and ions in host cell vesicles that promote genome release and efficient infection. The research was published in the Journal of Virology in August.
'A study like this makes it clear that even though we may think we know everything there is to know about the opioid response, we're actually just scratching the surface.' -- Kirill Martemyanov, PhD, Scripps Research Neuroscience Co-Chair
A recent study led by Dr. Radhika Venkatesan has identified that herbivores are capable of decoding the scent of a plant and using these cues to brace up their immunity.
An understanding of the molecular basis of differences in the incidence and survival of cancer between men and women may allow the discovery of specific and more effective treatments. The study, published in Science Advances, compares the brain tumours of male and female flies at the molecular level and identifies proteins responsible for the different degree of aggressiveness.
Scientists have found how to relieve a bottleneck in the process by which plants transform sunlight into food, which may lead to an increase in crop production. They discovered that producing more of a protein that controls the rate in which electrons flow during photosynthesis, accelerates the whole process.
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments.
A Nature Communications paper by Worcester Polytechnic Institute biologist Jagan Srinivasan has shown that a key biological component in the communication system of the nematode C. Elegans can be repurposed to take on a different job,. This critical finding about the workings of evolution could one day affect research into drug interactions, agricultural bio-engineering, and a better understanding of genetic inheritance through multiple generations.
Modern science and data sharing converged to underpin a study led by TGen that identified a gene associated with a rare condition that results in physical and intellectual disabilities of children. The results, published today in the American Journal of Human Genetics, suggest that rare variants in the gene DDX6 are associated with a significant disruption in the development of the central nervous system, governing such basic skills as the ability to walk and talk.
Finnish researchers have found cellular components in the epithelial tissue of the eye, which have previously been thought to only be present in electrically active tissues, such as those in nerves and the heart. A study at Tampere University found that these components, voltage-gated sodium (Nav) channels, are involved in the renewal of sensory cells in the adjacent neural tissue, the retina.
Voltage-gated ion channels at the surface of neurons and muscle cells control your every thought, movement; the very beating of your heart. For the first time, researchers at the EPFL's Blue Brain Project have mapped the behavior of the largest family of these channels. Published in Frontiers in Cellular Neuroscience, and freely available online as raw data, their pioneering work will power virtual drug discovery -- and, they hope, the first whole-brain simulation.