Despite the fact that people in sub-Saharan Africa are now living longer than they did two decades ago, their average life expectancy remains below that of the rest of the world population. A new study looked into the importance of various causes of death in Zambia and how eliminating the most prominent of these would impact life expectancy in the country.
a research team at Harvard's Wyss Institute for Biologically Inspired Engineering and the Massachusetts Institute of Technology (MIT) demonstrates the use of CRISPR as a control element in a new type of stimuli-responsive "smart" materials.
Healthy mice study real-time gut colonization and discovered a pivotal role for bacterial sex in the evolution of the mammalian microbiome. This discovery constitutes a paradigm shift and opens the possibility to design new therapies.
The cryoEM structure of a simian immunodeficiency virus protein bound to primate proteins shows how a mutation in early humans allowed our ancestors to escape infection while monkeys and apes did not. SIV's Nef protein forms a solid link between two primate proteins, tetherin and AP-2, forcing the destruction of tetherin, which normally prevents new SIV virions from budding off. A mutation in human tetherin disrupted binding, thwarting SIV budding -- until HIV evolved a work-around.
Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia. Globally, it is estimated that nearly two billion people suffer from zinc deficiency, but why this increases susceptibility to bacterial infection has not been well understood -- until now.
Researchers at the Yale School of Public Health (YSPH) have detected a large unreported Zika outbreak that occurred in Cuba during 2017, a year after Zika outbreaks peaked throughout the Americas.
New research finds that fish oil supplements have no effect on type 2 diabetes. Increased consumption of omega 3 fats is widely promoted globally because of a common belief that it will protect against, or even reverse, conditions such as diabetes. But a systematic review commissioned by the World Health Organization, to be published in the British Medical Journal, finds that omega 3 supplements offer no benefit.
New research has found that in 15 major cities in the global south, almost half of all households lack access to piped utility water, affecting more than 50 million people.
In a large survey in sub-Saharan Africa, adults who said they had paid a bribe for healthcare in the past year were more than four times as likely to report difficulty in obtaining care than those who had not paid bribes. Amber Hsiao and colleagues at the Technical University of Berlin, Germany, report these findings in the open-access journal PLOS ONE on Aug. 21, 2019.
The US each year sees more than 1,500 cases of malaria, and currently there is limited access to an intravenously administered (IV) drug needed for the more serious cases.