For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as stem cells of the airways because they can regenerate the airway epithelium in response to injury, this study may help accelerate research on diseases impacting the airway, including COVID-19, influenza, asthma and cystic fibrosis.
Researchers develop a new method to isolate specific cells, and in the process find a more robust fluorescent protein.
The critically endangered vaquita has survived in low numbers in its native Gulf of California for hundreds of thousands of years, a new genetic analysis has found. The study found little sign of inbreeding or other risks often associated with small populations.
People with diabetes -- especially those with diabetic kidney disease -- are among the most at risk for COVID-19. A new study peered inside the kidney cells of COVID-19 patients and diabetic kidney disease patients and made a surprising discovery: Similar molecular processes were activated in both sets of patients. The results suggest that diabetes may predispose patients to SARS-CoV-2 infection or more severe COVID-19 by spurring biological processes used by the virus to infect and replicate.
Researchers have discovered a gene that is critical for the development of Ewing sarcoma, a rare type of developmental cancer that presents in bones and soft tissues. Exploring the pharmacological inhibition of RING1B as a clinical therapy to treat Ewing sarcoma could open the door for new treatments for the rare disease.
This work examines requirements for introducing CAM and alternative water-saving pathways into C3 plants in different environments.
Recent successes of several FDA-approved therapeutic nucleic acids, together with the rapid preclinical progression of nucleic acid nanoparticles (NANPs), have made it apparent that immunological effects of NANPs must be carefully assessed to permit their successful clinical translation. Based on extensive studies, a standardized protocol allowing for the assessment of NANPs' pro-inflammatory properties in validated preclinical model, peripheral blood mononuclear cells, has been developed to be highly predictive of cytokine responses.
By examining the poop of the fringe-lipped bat (Trachops cirrhosus), a team at the Smithsonian Tropical Research Institute (STRI) encountered surprising results about its eating habits and foraging abilities.
Scientists analyzed genomic information from over 6,000 samples of SARS-CoV-2, the coronavirus behind the COVID-19 pandemic. Results show that early measures in states such as California and Washington were effective at limiting viral spread in the early phases of the pandemic.
Specific regions in cord blood DNA can help identify kids who might develop autism, according to a UC Davis MIND Institute study. The findings from the study may hold clues for early autism diagnosis and intervention.