Next-generation sequencing technology has made it easier than ever for quick diagnosis of plant diseases. "It's really exciting to see how sequencing technologies have evolved and how this new technology facilitates sequencing of entire genomes in such a short amount of time," said Yazmín Rivera, a plant pathologist with the United States Department of Agriculture's Plant Protection and Quarantine program, who recently published a research paper on the efficacy of Oxford Nanopore Technologies protocols.
CSHL scientists genetically profiled thousands of cells in normal breast tissue to establish what types of cells tend to become cancerous. This catalog can help researchers develop preventive therapies.
The study suggests that the SWI/SNF complex may be a tumour suppressor and DNA-RNA hybrids could be an important source of tumour generation
Researchers from Tokyo Medical and Dental University (TMDU) have demonstrated that delivering oxygen via the rectum as a gas or in an oxygen-rich liquid can support oxygen provision to organs and tissues during respiratory failure. Such "enteral ventilation" increased oxygenation, improved behavior and prolonged survival in experimental mouse and pig models of respiratory failure. Further research may allow its clinical application in human patients as a less invasive alternative to ventilators and artificial lungs.
Scientists from China have sequenced and analyzed the genome of lavender to provide insights into what causes its distinct aroma. Their findings shed light into the evolution of this uniquely fragrant plant, which could pave the way for creating improved lavender varieties besides adding to existing knowledge on the evolution, phytochemistry, and ecology of Lamiaceae, the plant family to which lavender belongs.
Climate change is exacerbating problems like habitat loss and temperatures swings that have already pushed many animal species to the brink. But can scientists predict which animals will be able to adapt and survive? Using genome sequencing, researchers from McGill University show that some fish, like the threespine stickleback, can adapt very rapidly to extreme seasonal changes. Their findings could help scientists forecast the evolutionary future of these populations.
Biologists have revealed for the first time the genetics linking pheromone signals produced by female moths and the neuronal response driving male attraction to females. The ability to predict mate choice will help in understanding how species diverge, and how to control agricultural pests.
The wild California condor population dropped to 22 before rescue and captive breeding allowed reintroduction into the wild. A new assembly of the complete genome of the bird reveals some inbreeding as a result, but overall high genomic diversity attesting to large populations of condors in the past, likely in the tens of thousands. Comparison to Andean condor and turkey vulture genomes reveals declines in their populations also, and lower genomic diversity than California condor.
Research conducted by an international team of scientists discovered a mechanism that leads to Herceptin resistance, representing a significant clinical obstacle to successfully treating HER2-positive breast cancer. They also identified a new approach to potentially overcome it.
SARS-CoV-2 is critically dependent on a special mechanism for the production of its proteins. A collaborative team led by a research group at ETH Zurich obtained molecular insights into this process and demonstrated that it can be inhibited by chemical compounds, thereby significantly reducing viral replication in infected cells.