Researchers have developed a new non-invasive method to count individual fish by measuring the concentration of environmental DNA in the water, which could be applied for quantitative monitoring of aquatic ecosystems.
Using state-of-the-art approaches coupled with bio- and cheminformatics and machine learning, researchers at the GEOMAR Helmholtz Centre for Ocean Research Kiel have succeeded in discovering new, bioactive components of the Baltic Sea Baltic Sea seaweed Fucus vesiculosus and its fungal symbiont against infectious bacteria or skin cancer.
In an article published today in Science, a multidisciplinary research team from more than 10 universities and research institutes outlines how integrating a more diverse set of species and environments could enhance the biomedical research cycle.
Some people are better protected than others against urinary tract infections. This may be because their bodies produce more of a protein called uromodulin. An interdisciplinary research team has now found out exactly how this helper protein brings relief when nature calls and how this knowledge might benefit the treatment and prevention of these painful inflammations.
Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these proteins suppress B cell function and conversely, that Tet2/Tet3 knockout mice develop a mild form of systemic lupus erythematosus due to hyperactivation of T cells. These findings could help develop a novel treatment for autoimmune diseases.
Stem cells have been holding great promise for regenerative medicine for years. However, one of the main limitations in the application of these therapies is the quality of the stem cells that can be generated in the laboratory. Now, a team from the Spanish National Cancer Research Centre (CNIO) has developed a new, simple and fast technology that enhances in vitro and in vivo the potential of stem cells to differentiate into adult cells.
By mapping molecular changes in the genome over time, UC San Diego researchers developed a formula to more accurately compare dog age to human age -- a tool that could also help them evaluate how well anti-aging products work.
In a study that takes another look at histones' origins, researchers report these proteins, known for DNA-packing, may have evolutionary roots in early life in helping to maintain the use of metals like copper - fundamental for biological processes, but which became toxic to eukaryotes as they adapted to global oxygenation.
For the first time, scientists have shown that the bacterium that causes the tick-borne disease anaplasmosis interferes with tick gene expression for its survival inside cells and to spread to a new vertebrate host. Girish Neelakanta of Old Dominion University and colleagues report these findings in a study published July 2nd in PLOS Genetics.
Scientists have used advanced technology to 'micro-dissect' the first brain cells to perish in Alzheimer's disease. The result is a short list of genes that could represent new drug targets.