DOAC (direct oral anticoagulant) pills are used in the treatment of atrial fibrillation by preventing blood clots. Even though blood clots are thought to contribute to complications from the new coronavirus infection, users of this class of drug do not seem to be protected against severe COVID-19, reports a large Swedish registry study from Karolinska Institutet published in The Journal of Internal Medicine.
Curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined. However, the current diagnostic techniques vary in reliability and relevance, so an understanding of which test is most appropriate for a given circumstance is necessary to avoid false reports. Researchers evaluated the available diagnostic techniques and determined key steps required for better testing moving forward. They present their findings in the journal APL Bioengineering.
The recent serious outbreak of Covid19 has required urgent medical treatments for numerous patients. No clinically active vaccines or antiviral agents are available for Covid19. According to several studies, Chloroquine (CQ) and Hydroxychloroquine (HCQ) have shown promises as Covid19 antiviral especially when administered with Azithromycin (AZM).
A team co-led by a scientist at the University of California, Riverside, has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine design.
Chemical compounds in foods or beverages like green tea, muscadine grapes and dark chocolate can bind to and block the function of a particular enzyme, or protease, in the SARS-CoV-2 virus, according to a new study by plant biologists at North Carolina State University.
Using post-mortem tissue samples, researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19. The results show that SARS-CoV-2 enters the brain via nerve cells in the olfactory mucosa. For the first time, researchers have been able to produce electron microscope images of intact coronavirus particles inside the olfactory mucosa.
A research team co-led by a scientist at the Hong Kong University of Science and Technology has developed a method to study how HIV mutates to escape the immune system in multiple patients, which could inform HIV vaccine design.
Survivors from a wide range of cancers are more likely than people in the general population to be hospitalised or die from seasonal influenza even several years after their cancer diagnosis, according to new data published in EClinicalMedicine. Given that flu and COVID-19 are both epidemic respiratory viruses with broadly similar risk factors, the findings suggest that cancer survivors are also likely to be at raised risk of severe COVID-19 outcomes.
Scientists have conducted a 'molecular dissection' of a part of the virus that causes foot-and-mouth disease, to try and understand why the pathogen is so infectious. A team of scientists from the University of Leeds, UK, and University of Ilorin, in Nigeria, has investigated the significance of the unusual way the virus's genome - or genetic blueprint - codes for the manufacture of a protein called 3B. The protein is involved in the replication of the virus.
Scientists at Keele University and King's College London have found that 64% of people would be likely to have a COVID-19 vaccination when one became available.