Researchers from the Miami University in Ohio have optimized a new technique that will allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria. This technique, called native state mass spectrometry, provides a quick way for scientists to identify the best candidates for effective clinical drugs, particularly in cases where bacteria can no longer be treated with antibiotics alone.
Smartphone apps have proved invaluable for helping people manage chronic pain during the COVID-19 pandemic, but researchers warn that the need for information sharing and education in this area is being neglected.
By cleverly combining complementary sequencing techniques, researchers of Ghent University, together with Baylor College of Medicine and the world's leading sequencing company, Illumina, have deepened our understanding of the function of known RNA molecules and discovered thousands of new RNAs. A better understanding of our transcriptome is essential to better understand disease processes and uncover novel genes that may serve as therapeutic targets or biomarkers.
While stents are highly effective, scarring or clotting of unhealed stents can occur and lead to complications. Approaches to understand stent healing based on their biological clotting status is unavailable in patients. To devise a potential solution, Dr. Jason McCarthy, an Associate Professor at MMRI, and his team developed a fluorescent probe that binds to activated platelets, allowing the potential for clinicians to proactively treat patients before the development of occlusive stent clotting or scarring.
Researchers have designed a device that delivers two medications that help stop HIV transmission.
People with the rare autoimmune disease scleroderma, who likely experience more serious isolation during a global pandemic, saw their anxiety and depression improve after receiving online mental health intervention through an international study. Researchers say the program could be extended to many vulnerable patient populations moving forward.
The study found that rebates were associated with increases in out-of-pocket costs for patients by an average of $6 for those with commercial insurance, $13 for Medicare patients and $39 for the uninsured.
Financial toxicity, the financial strain experienced by patients accessing health care, impacts a large population of cancer patients according to prior research. A new study, published in JACC: CardioOncology, finds financial toxicity is often greater among heart disease patients compared to cancer patients, and those with both conditions suffer the highest burden.
While the United States faces a nationwide nursing shortage, a recent study at the University of Missouri found rural Missouri counties experience nursing shortages at a greater rate than the state's metropolitan counties.
A University of Tsukuba study examined a massive national claims dataset in search of regional and socioeconomic inequalities in the use of dental care services in Japan. This examination of millions of pieces of data found periodontal care and outreach services showed the widest regional inequalities. People in areas with lower education and income were more likely to seek treatment after dental diseases progress. More clinics and higher education and incomes correlated with earlier treatment.