Atomic imaging and AI offer new insights into motion of parasite behind sleeping sickness
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Apr-2025 02:08 ET (24-Apr-2025 06:08 GMT/UTC)
African sleeping sickness is a serious infection caused by a parasitic microbe called Trypanosoma brucei.
Using an imaging technique called cryo-electron microscopy along with artificial intelligence, a team at the California NanoSystems Institute at UCLA mapped the hairlike flagellum that the microbe uses to propel itself, identifying 154 composite proteins.
Findings revealed that the parasite moves in a distinctive style, similar to a dragon boat, with unique adaptations that are essential to its ability to infect its hosts.
Using their novel FRESH 3D bioprinting technique, which allows for printing of soft living cells and tissues, Carnegie Mellon’s Feinberg lab has built a first-of-its-kind tissue model entirely out of collagen.
In a study published in Ophthalmology, physicians followed 562 patients in the United States and India over a three-month period to identify risk factors that could be easily managed with early intervention.
Maria A. Woodward, M.D., an associate professor of ophthalmology and visual sciences and a member of the Institute for Healthcare Policy and Innovation, answers questions about what causes microbial keratitis, symptoms and preventative measures.