Investigators from Mass General Brigham and collaborators in the U.S. and Europe analyzed data from three prospective cohorts comprising 97 patients who underwent rs-fMRI after injury, finding that early communication between three pairs of brain regions is associated with favorable six-month functional outcomes.

Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells. A new study from researchers at Georgetown University Medical Center found that this form of epilepsy can be treated in mice by either genetically or pharmaceutically eradicating the aging cells, thereby improving memory and reducing seizures as well as protecting some animals from developing epilepsy.

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors. 

A new study by researchers at the Icahn School of Medicine at Mount Sinai suggests that artificial intelligence (AI) could help predict which critically ill patients on ventilators are at risk of underfeeding, potentially enabling clinicians to adjust nutrition early and improve patient care. Details of the study were published in the December 17 online issue of Nature Communications.