Adenocarcinoma cells (IMAGE)
Caption
Lung adenocarcinoma tumor cells (green) and macrophages (red) accumulate in the lungs of control mice (left), but expansion of the tumor cells is hindered in macrophage PPARγ knockout mice (right), since the macrophages can’t be metabolically coopted by tumor cells. Cellular cholesterol is visualized in yellow.
Credit
Salk Institute
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