Comparative PET/CT imaging in heterotopic HepG2 xenograft mouse model. (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

Comparative PET/CT imaging in heterotopic HepG2 xenograft mouse model.

Caption

Comparative PET/CT imaging in heterotopic HepG2 xenograft mouse model. (A–C) Summed PET/CT images from 20 to 45 min after intravenous injection of [18F]4-FDF (A), [18F]6-FDF (B), or [18F]FDG (C). Sagittal sections, coronal sections, and maximum-intensity projections are shown, in addition to axial sections at level of brain, heart, liver/kidneys, and hips. (D) Fold change in area under curve for entire time–activity curve in Supplemental Figure 2 for [18F]6-FDF and [18F] FDG normalized to values for [18F]4-FDF. Purple represents an increase in AUC, and blue represents decrease in area under curve. %ID = percentage injected dose; AUC = area under curve; MIP = maximum-intensity projection.

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Image created by A Kirby and A Shuhendler, University of Ottawa and University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

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