Elevated TRMT10C protein levels in Alzheimer's disease (IMAGE)
Caption
Elevated TRMT10C protein levels in Alzheimer's disease result in methylation of mitochondrial mRNA and subsequently in the suppression of the synthesis of a subunit protein of complex I of the respiratory chain. The consequent reduction of the synthesis of the ND5 subunit protein leads to mitochondrial dysfunction.
Credit
ill./©: Kristina Friedland / JGU
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CC BY-NC-ND