Chemographic representation of an “address” within the nECM surrounding the neuron and glial cells (IMAGE)

The Hebrew University of Jerusalem

Chemographic representation of an “address” within the nECM surrounding the neuron and glial cells

Caption

The "address" is depicted as a electron-rich square capable of binding a metal cation and trapping a signaling molecule like a neurotransmitter (NT) or a gliotransmitter (GT) to create a metal-centered ternary complex that functions as a cognitive unit of information (cuinfo). This cuinfo serves as the fundamental unit of memory, including emotional memory, and represents the biochemical embodiment of the molecular unit of memory (MMM) concept introduced by Zeltzer et al., 2022.

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Marx and Gilon

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