Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance (IMAGE)

St. Jude Children's Research Hospital

Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance

Caption

Corresponding author Taosheng Chen, PhD (left), co-first author Sergio Chai, PhD (center) and co-author Shyaron Poudel, St. Jude Department of Chemical Biology & Therapeutics investigated the inhibitor/activator binding mechanisms of pregnane X receptor (PXR), a protein implicated in drug metabolism.

Credit

St. Jude Children's Research Hospital

Usage Restrictions

No cropping

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.