CD8+ T cells mediate the immune response to human-induced pluripotent stem cell-derived cardiomyocyte sheets in mice models (IMAGE)
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Human-induced pluripotent stem cell-derived cardiomyocyte sheets can be a life-saving intervention for patients with advanced cardiovascular disease. Administration of immunosuppressive agents to counter CD8+ T cell-triggered tissue rejection can improve treatment outcomes.
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Ryu Matsumoto from Juntendo University Graduate School of Medicine
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