Molecular imaging of 7-wk-old girl with neuroblastoma. (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

Molecular imaging of 7-wk-old girl with neuroblastoma.

Caption

Figure 3A. [18F]MFBG LAFOV PET/ULD CT (top) and [123I]MIBG scintigraphy with SPECT/LD CT images (bottom) of 7-wk-old girl with neuroblastoma. [18F]MFBG image shows intraspinal and bone marrow involvement not seen on [123I]MIBG image. [18F]MFBG PET/ULD CT image shows uptake in tumor in right hemithorax with intraspinal involvement with direct extension into neural foramina and spinal canal between thoracic vertebrae 4/5 and 5/6 (top red arrow), several liver lesions (middle red arrow), and in bone marrow of right tibia (bottom red arrow). [123I]MIBG scintigraphy with SPECT/LD CT image shows only large thoracic tumor (top purple arrow) and liver metastases (bottom purple arrow). Spinal involvement and bone marrow involvement could not be identified on [123I]MIBG scintigraphy with SPECT/LD CT. 

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Image courtesty of The Journal of Nuclear Medicine.

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