aGPCR structure (IMAGE) University of Chicago Caption Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Credit Eric Smith Usage Restrictions Please credit License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.