fig 1 (IMAGE)

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fig 1

Caption

Fig 1: Long-term EGCG intake alleviates aging-related cardiomyocyte apoptosis and mitochondrial damage. (A, B) Representative histology of heart tissue sections stained with hematoxylin-eosin stain and Masson's trichrome stain (yellow arrows collagen fibrosis; scale bar: 100 μm). (C) TUNEL stain for evaluation of cardiomyocyte apoptosis (red arrows apoptotic cells; 400 × ). (D) Transmission electron microscope (TEM) for the display of myocardial ultrastructure (blue arrows damaged mitochondria and orange arrows twisted myofilaments; 10000 × ). (E–G) Quantitative analysis of myocardial fibrosis, cardiomyocyte apoptosis, and mitochondrial destruction (n = 3–4). All results are represented as mean ± standard deviation. ∗∗∗P < 0.001.

 

 

 

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Genes & Diseases

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