Unique model of rare epileptic disease helps pinpoint potential treatment route (IMAGE)
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UBA5 disorder is considered an ultra-rare condition which affects brain function, but a new cortical organoid model presented in Science Translational Medicine today reveals key defects which may be targetable. Pictured is first author Helen Chen, PhD, formerly of the Pediatric Translational Neuroscience Initiative and Department of Cell & Molecular Biology, corresponding author Heather Mefford, MD, PhD, and Emily Bonkowski, Pediatric Translational Neuroscience Initiative and Department of Cell & Molecular Biology, and Aidan Blan, formerly of the Pediatric Translational Neuroscience Initiative and Department of Cell & Molecular Biology.
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St. Jude Children's Research Hospital
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