Changes in FVC ± 95% CI after 12 weeks of Rentosertib treatment compared to baseline (IMAGE)

InSilico Medicine

Changes in FVC ± 95% CI after 12 weeks of Rentosertib treatment compared to baseline

Caption

(left) The absolute change in FVC ± 95% CI.
(center) The absolute change in FVC ± 95% CI ANCOVA model with multiple imputation assuming missing at random (MAR).
(right) Changes in FVC ± 95% CI after 12 weeks of treatment compared to baseline excluding n = 1 patient from the placebo group and n = 1 patient from the Rentosertib 30 mg QD group who exhibited >600 mL difference between screening and baseline FVC measurements, making uncertain the baseline FVC values in those patients.

Credit

Nature Medicine

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License

Public Domain

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