Multifunctional and Scalable Nanoparticles for Bimodal Image-Guided Phototherapy in Bladder Cancer Treatment (IMAGE)
Caption
- Pyropheophorbide a–bisaminoquinoline conjugate lipid nanoparticles (PPBC LNPs), formulated with lipid-based excipients and assembled using microfluidics, exhibit excellent biocompatibility and stability, indicating promise for clinical applications.
- PPBC LNPs possess remarkable photoacoustic and fluorescence imaging capabilities, enabling high-resolution, deep tissue penetration and high sensitivity imaging for tracking drug biodistribution and phototherapy efficacy.
Credit
Menghuan Tang, Sohaib Mahri, Ya-Ping Shiau, Tasneem Mukarrama, Rodolfo Villa, Qiufang Zong, Kelsey Jane Racacho, Yangxiong Li, Yunyoung Lee, Yanyu Huang, Zhaoqing Cong, Jinhwan Kim, Yuanpei Li, Tzu-Yin Lin.
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CC BY-NC-ND