(IMAGE)

Innovation Center of NanoMedicine

Caption

Through the precise molecular design of cationic polypeptides, we have prepared a new dynamic nanomedicine (or nanomachine) that loosely encapsulates a single molecule of oligonucleotide drug. When administered intradermally, the nanomedicine can efficiently deliver the oligonucleotide payload to tumor-draining (sentinel) lymph nodes, enhancing cancer immunotherapy through activation of immune cells.

Credit

Miyata Lab, University of Tokyo

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