DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders (IMAGE)
Caption
Figure 1. Association between entropy, biological age, and biomarkers across neurological conditions. (A) Boxplots of entropy across different age groups (only significant P-values are annotated: P < 0.05 = *, P < 0.01 = **, P < 0.001 = ***). (B) Behavior of summed dolichol concentration through age, with a 95% confidence interval. (C) Predicted values of the models for all samples, including groups with no neurological disorder, autism, schizophrenia, and Down syndrome. (D) Boxplot comparing age acceleration across the different groups (Only significant P-values are annotated: P < 0.05 = *, P < 0.01 = **, P < 0.001 = ***).
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Copyright: © 2025 Latumalea et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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