Phosphatase Inhibitors: Targeting Cancer and Immune Cells (IMAGE)

Sichuan International Medical Exchange and Promotion Association

Phosphatase Inhibitors: Targeting Cancer and Immune Cells

Caption

Druggable phosphatases in cancer and immune cells, with examples of their corresponding drugs. Structures of allosteric inhibitors targeting PP2A, PRL3, DUSP1/6, and SHP2 in cancer cells (left). Structures of catalytic inhibitors targeting SHP2, SHP1, PTPN2, PTP1B, and PTPN22 in immune cells (right). Figure created using Canva (www.canva.com).

Credit

Khaled Barakat

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