Insulin action in the peripheral and the brain. (IMAGE)
Caption
Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within the central nervous system to regulate both direct effects within the brain and indirect signaling events that reflect back to the periphery. Its roles are highly varied and may reflect its evolutionary history as a growth regulator. In the periphery, insulin influences all tissues but predominantly affects major metabolic tissues, such as adipose tissue, liver, and skeletal muscle.
Credit
Dr. Mary E. Herman, Independent Health Researcher and Educator: Building Global Research Competency, Guatemala. Image Source Link: https://onlinelibrary.wiley.com/doi/10.1002/nep3.70008#
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