Generation of the Artificial Ureter Tissues (IMAGE)
Caption
A method was developed to induce ureteral stromal progenitor cells from pluripotent stem cells (red arrow), enabling the successful creation of artificial ureter tissue by combining them with ureteral epithelial progenitor cells derived from mouse embryos or induced from pluripotent stem cells.
Top right image: Ureter organoid formed by combining ureteral stromal progenitor cells derived from mouse ES cells with ureteral epithelial cells derived from mouse embryos.
Bottom right image: Cross-section of the created ureter organoid, showing differentiation similar to that of natural ureters in the body.
Credit
Ibi et al.
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License
CC BY-NC