Figure 1. Therapeutic effects of KDS2010 in an animal model of spinal cord injury (IMAGE)

Institute for Basic Science

Figure 1. Therapeutic effects of KDS2010 in an animal model of spinal cord injury

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The selective MAOB inhibitor KDS2010 significantly improved functional recovery in a spinal cord injury animal model. Treated animals showed marked restoration of behavioral scores and locomotor abilities, and these effects were sustained over time (b, d). While control animals with injury alone exhibited severe hindlimb paralysis, the KDS2010-treated group demonstrated clear recovery of motor function and improved walking performance. In particular, gait analysis using an automated locomotion assessment system revealed near-normal motor performance (e).

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Institute for Basic Science

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