WNT signaling pathway inhibitors (IMAGE)

Sichuan International Medical Exchange and Promotion Association

WNT signaling pathway inhibitors

Caption

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation. These agents can be broadly classified based on their molecular targets, which include: (1) Porcupine inhibitors, (2) WNT/FZD antagonists, (3) LRP5/6 inhibitors, (4) DVL inhibitors, (5) TNKS inhibitors, (6) CK1 agonists, (7) β-catenin/TCF transcriptional complex inhibitors, and (8) CBP inhibitors.

Credit

Jing Li

Usage Restrictions

Marked by the credited

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.