Overview of breast cancer initiation and progression. (IMAGE)
Caption
Breast cancer pathogenesis is influenced by various molecular and environmental risk factors. It begins through the mutation of oncogenes, tumor suppressor genes, and dysregulation of key cell signaling pathway, which lead to normal breast epithelium to hyperplasia. After hyperplasia, cells undergo to preinvasive stage (carcinoma in situ) and eventually to invasive carcinoma. [Created using BioRender.com.]
Credit
Shams Tabrez
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Original content