Osteosarcoma invading normal bone (IMAGE)
Caption
A confocal microscopy image of mouse bone cancer, or murine osteosarcoma (outlined in gray), invading normal bone (blue). Peripheral nerves (green) and blood vessels (red) sprout around the tumor, forming a supportive environment for its growth and spread. This image is the cover photo for the Oct. 28, 2025, issue of PNAS.
Credit
Sowmya Ramesh, Johns Hopkins Medicine
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