L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice (IMAGE)
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Figure 9. EDL muscle fiber cross-sectional area after the three-month intervention period. (A) Representative images of EDL muscle histological sections stained for dystrophin for quantitation of myofibers. The scale bar represents 100 μm. (B) Quantitation of the total number of EDL myofibers. (C) Average EDL myofiber cross-sectional area (CSA). (D) The frequency distribution of EDL myofiber CSA. Inlay: Superimposed myofiber frequency distribution curves at 250 μm binning. Two-way ANOVA, p>0.05. n = 8 CTRL, n = 8 VWR, n = 8 CTRL+L-BAIBA, n = 8 VWR+L-BAIBA. Mean ± SD.
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